Read the dictionary definition of nettle. All definitions for this word.
1. any of numerous plants having stinging hairs that cause skin irritation on contact (especially of the genus Urtica or family Urticaceae)
2. cause annoyance in; disturb, especially by minor irritations
1. Mosquitoes buzzing in my ear really bothers me
2. It irritates me that she never closes the door after she leaves
3. sting with or as with nettles and cause a stinging pain or sensation